Carrier Determination in a Hemophilia B Family Using Single Strand Conformation Polymorphism (SSCP) and Sequencing
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Carrier determination in a Hemophilia B family using single strand conformation polymorphism (SSCP) and sequencing
Hemophilia B is an X-linked recessive bleeding disorder caused by heterogeneous mutations in factor IX gene. In about one-third of cases it arises by a new mutation in germ-line cells. In this study carrier testing was performed for females of a family with only one affected individual by single strand conformation polymorphism (SSCP). Results indicated that the SSCP band shift in the propositu...
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عنوان ژورنال
دوره 2 شماره 2
صفحات 132- 135
تاریخ انتشار 2004-04-01
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